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While lipophilicity, dipole moment, and size are factors that influence the ability of a compound to enter the hydrophobic core of a cell membrane, the lipid bilayer environment is too chemically complex, fluid, and heterogeneous for these indicators alone to provide accurate estimates of transport kinetics

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The CAS number for Dihexa is 1401708-83-5

Even a few hours at ambient temperature can significantly reduce peptide integrity

Then, we used homologous and heterologous orthotopic xenograft mice model to evaluate the role of cancer cell intrinsic HEXB in promoting the tumorigenicity of GBM cells