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in this context, how potent the active metabolite is with regard to the parent drug is also a matter of importance
doi: 10.3390/genes12101620 39 KozieE.Otulak-KozieK.BujarskiJ
Promotes skin hydration and moisture retention
Microarray gene expression profiling in colorectal (Hct116) and hepatocellular (Hepg2) carcinoma cell lines treated with melicope ptelefolia leaf extract reveals transcriptome profiles exhibiting anticancer activity
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Its most well-characterized mechanism involves stimulating collagen and glycosaminoglycan synthesis in skin fibroblasts, which underlies its effects on skin elasticity, firmness, and wound repair
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