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Any structural alterationoxidation of the tryptophan residue, hydrolysis of the peptide backbone, or disruption of the disulfide bridge in the cyclic portionrenders the molecule inactive
Methods Animals Eight-week-old female NOD/ShiLtJ mice (NOD, strain code: 001976) and NOD.CB17-Prkdc Scid /J mice (NODscid, strain code: 249809) were purchased from Charles River (Italy, breeding unit A005)
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Meniscus Injuries A meniscus tear presents a different challenge altogether
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