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Description

Pathol Res Pract 260:155374

Covalent modification at Cys151 dissociates the electrophile sensor Keap1 from the ubiquitin ligase CUL3

Expert Opin Med Diagn 2011

In Parkinson's disease, dopamine-producing neurons in an area of the brain called the substantia nigra die off as a result of free radical-based damage