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& Kasinski, A

The consistent results from sensitivity analyses using the Cox proportional hazards model with alternative sets of covariates and various exclusion criteria confirmed the robustness of our findings (Supplemental Table 8)

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BRCA1, which regulates cell cycle progression, DNA damage signalling and repair, and maintenance of genomic integrity, interacts with NRF2 either directly, through its ETGE motif, preventing KEAP1-dependent ubiquitination of NRF2 and protecting cells against OS, or indirectly, through the interaction with CBP or with c-Myc [186]

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