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This fact paved the way for the development of a GIP receptor agonist-based therapy for T2DM, looking also for the possibility of finding a combined GLP-1/GIP receptor agonist
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Research also suggests it helps with the integration of bone grafts, which could be beneficial for certain surgical procedures
While human clinical trials remain limited, the depth of animal research, consistency of positive findings across multiple study designs, and extensive community experience create a reasonable basis for therapeutic use
For example, in the STEP UP Diabetes trial, participants taking 7.2 mg of semaglutide weekly lost an average of 13.2% of their initial weight, compared to 10.4% for those on the standard 2.4 mg weekly dose
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