A new preclinical study at Northwestern Universitys Feinberg School of Medicine found that disrupting complex I function in mouse dopaminergic neurons led to progressive PD-related motor deficits, with loss of dopamine release in the substantia nigra being critical for motor deficits (40)
A higher weekly dose appears to reduce the progression of chronic kidney disease and cardiovascular events seen in patients with Type-2 diabetes
It seems advised that such studies use other established sugar replacers like polyols or other monosaccharides as a reference
But what about prescription weight-loss medications
T., Flavius, M., Rosca, A., Constantin, C., Scurtu, A., Moriczi, R., & Muresan, M
Pastoris O, Minzioni G, Ceriana P, Barzaghi N (1998) Effect of L-CARNITINE on myocardial metabolism: results of a balanced, placebo-controlled, double-blind study in patients undergoing open heart surgery