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The activation of non-canonical pyroptotic pathways frequently occurs upon gram-negative bacterial infection (163)

Supports overall gut health by reducing inflammation and healing gastrointestinal tissues

2019;7:S62

Pagnussat GC, Yu HJ, Ngo QA, Rajani S, Mayalagu S, Johnson CS, Capron A, Xie LF, Ye D, Sundaresan V (2005) Genetic and molecular identification of genes required for female gametophyte development and function in Arabidopsis

Required to prevent cells from ferroptosis, a non-apoptotic cell death resulting from an iron- dependent accumulation of lipid reactive oxygen species (PubMed:24439385)

B12 is primarily found in animal-based foods like meat, eggs, and dairy, which makes it a common deficiency in vegetarians, vegans, and those with absorption issues