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Cystic fibrosis, usually due to severe mutation in bothalleles of the cystic fibrosis transmembrane conductance regulator ( CFTR ) gene, causes an accelerated non-calcific form of chronic pancreatitis that begins in utero : oxidative stress and inflammation are now regarded as integral features of the disease, driven by unfolded CFTR via the ER stress-UPR system (121, 177)
This is a great question because it gets to the heart of how your body processes nutrients
Zghonda et al
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Schwarz, B
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