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J Environ Sci 32:2634 Lopaschuk GD, Ussher JR, Folmes CDL, Jaswal JS, Stanley WC (2010) Myocardial fatty acid metabolism in health and disease

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In women, up to 12 months of use showed no evidence of tissue changes or serious issues emerging.There was no accumulation of effects on blood pressure or heart rate with ongoing use the cardiovascular effects remained transient

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