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Health conditions that may increase eligibility For adults with a BMI of 27 or higher, having one of the following weight-related conditions may qualify you for a prescription: Type 2 diabetes High blood pressure (hypertension) High cholesterol (dyslipidemia) Heart disease Obstructive sleep apnea Who should not take Foundayo A clinician will evaluate your full medical history before prescribing

Lower Metabolic Risk: Preferred for Metabolically Vulnerable Patients Bupropion (Wellbutrin): Unique among antidepressants for consistent weight loss or neutrality Average 2-5 pound weight loss in studies Mechanisms include dopamine/norepinephrine effects, possible appetite suppression Does NOT cause sexual dysfunction (unlike SSRIs) Activating (helps energy, can improve motivation) No significant adverse metabolic effects on glucose or lipids Limitations: Can worsen anxiety (not appropriate for patients with primary anxiety disorders) Contraindicated in seizure disorders Contraindicated in active eating disorders (anorexia, bulimia) due to seizure risk Can cause insomnia if taken too late in the day Clinical bottom line: First-line choice for depression in patients with obesity or metabolic concerns (unless specific contraindications)

Otherwise, the main difference is how you administer it

These timelines reflect branded medications in controlled environments

The question becomes: do you need to stay at the maximum dose to maintain results, or can you step down

What we've seen with these medications is that oftentimes the stomach is not empty, and then they're at risk for aspiration." Aspiration is a significant complication where a patient inhales stomach contents into the lungs