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The main outcomes were the incidence of diabetes and cardiovascular disease, where the latter included hospitalized myocardial infarction, stroke, or heart failure
The GLP-1RA exenatide was shown to significantly lower BMI and 2-hour glucose in adolescents with obesity, in the placebo-controlled, randomized controlled trial Combat-JUDO
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Recent advances have expanded the use of MNs for GLP-1 receptor agonists, which are traditionally limited by poor oral bioavailability and require frequent subcutaneous injections
A SWATH-MS analysis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome peripheral blood mononuclear cell proteomes reveals mitochondrial dysfunction