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Serum CHI3L1 levels were measured using chemiluminescence enzyme-linked immunoassay
Zepbound is another highly effective treatment, demonstrating potential weight loss of up to 22%, utilizing dual-action on GIP and GLP-1 pathways
SYNERGY-NASH: Tirzepatide and metabolic steatohepatitis (MASH) SYNERGY-NASH (Loomba et al., NEJM 2024, NEJMoa2401943, PMID 38856224) is a phase 2 trial in 190 patients with metabolic steatohepatitis (MASH) and biopsy-proven stage 2 or 3 fibrosis
Additionally, in December 2024, Zepbound gained FDA approval for treating moderate to severe obstructive sleep apnea (OSA) in adults with obesity
References StatPearls (NCBI Bookshelf) Farzam K, Patel P
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