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The psychological impact of treatment duration should not be overlooked
The incidence of pancreatitis was numerically higher among those on a GLP-1 RA (2.7% placebo, 1.2% OCA 10 mg, 1.3% OCA 25 mg) compared with the overall safety population (0.8% placebo, 0.6% OCA 10 mg, 1.0% OCA 25 mg)
When it comes to risk, the FDA has deemed that these versions can be hazardous
Another recently published review (Wu et al., BMC Medicine, 2025 ) looked at a range of studies on this subject to provide an overview of what happens when these medications are stopped
As a triple agonist, it targets glucose-dependent insulinotropic polypeptide, glucagon-like peptide-1, and glucagon receptors
PlexusDx sources all compounded medications exclusively from licensed 503A compounding pharmacies, which operate under strict FDA oversight and state pharmacy board regulations
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