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Overall, the analysis showed that stopping the drugs doesn't lead to significant weight regain, mainly because many patients tend to restart the original medication or try an alternative obesity treatment

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GLP-1 receptor agonists and the gut microbiome: evidence from experimental models Preclinical models consistently demonstrate that GLP-1 RAs can reshape the gut microbiota composition toward a healthier profile ( Bacillota , while increasing Bacteroidota , resulting in a marked decrease in the Bacillota/Bacteroidota ratio

Polat M, stn H

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