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Although these drugs have been used to treat type 2 diabetes for nearly two decades, it was not until 2021 that the US FDA approved them for treating obesity

Moawad AR, Tan SL, Xu B, Chen HY, Taketo T

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According to a recent retrospective clinical study, patients with various statuses of HER2 (heterogenous, reduced, and loss) benefited from T-DXd, 424 while these patients showed limited response to T-DM1

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Presented for research literature review only Pola P et al