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For example, studies using radiolabeled exenatide have shown that it can readily enter the mouse brain, though this central uptake appears to diminish at higher doses (Kastin and Akerstrom, 2003)
For those looking at any type of GHK-Cu treatment, these are what you should think of immediately
Also, histidine 96 and histidine 111 (human PrP numbering) that are located outside the octarepeat region, are also actively involved in PrP-Cu 2+ binding (Snchez-Lpez et al., 2018)
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