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A phase 2, double-blind, placebo-controlled trial randomized patients with moderate-severe PDPN to subcutaneous fulranumab or placebo

Important Note Severe, persistent abdominal pain radiating to the back requires immediate medical evaluation as this may indicate pancreatitis, a rare but serious complication

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For Weight Loss: Significant weight loss typically occurs over several months, with many patients achieving substantial results within 6-12 months when combined with lifestyle changes

The main challenge is bioavailability