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30 Third, an open-label Phase 1 trial compares bioavailability of levodopa between subcutaneous delivery of ND0612 and nasojejunal-infused LD-CD intestinal gel, and seeks to identify optimal concentration of carbidopa

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In the present study, the cecal microbiome differed significantly across treatment groups, despite tightly controlling for several variables known to alter the microbiome in rodents

In addition, the surface charge of nanoparticles is crucial for neuronal targeting