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The major active metabolite, 5-hydroxy saxagliptin, is only 2-fold less potent than its parent molecule (Capuano et al., 2013)

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[1] [2] As a once-weekly injectable medication, tirzepatide works through multiple complementary mechanisms

Thus, the expression of downstream NOX4/ROS/VEGF signaling pathway-related proteins is activated and the proliferation of breast cancer cells is increased, whereas the proliferation of breast cancer cells is inhibited in the control group with the addition of inhibitors