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At a genome-wide significant level, three loci (ABCG2, SLC2A9, and CUX2) have been identified in association with renal urate overload, whereas four loci (ABCG2, SLC2A9, CUX2, and GCKR) have been linked to renal urate underexcretion

Dominant Therapeutic Indication : Primary weight management is anticipated to represent nearly 54% of total market demand in 2026 , supported by increasing physician recognition of obesity as a chronic disease

[11] Your prescriber will individualize both the route (IV or IM) and the timetable based on your weight, kidney function, and overall clinical picture

Science 324, 742744

Early use helps achieve significant weight loss and improved metabolic outcomes, which can reduce the need for more invasive treatments later

The program begins July 1, 2026 and is scheduled to end December 31, 2027