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A 2014 systematic review and meta-analysis of 14 RCTs reported that certain probiotics produced small improvements in gut transit time and stool frequency, with effects varying by strain.[5] Since semaglutide also causes constipation (and constipation can contribute to bloating), this category has indirect relevance, though the trials were not in semaglutide users
Most published studies are limited to rodent models or cell cultures, leaving a gap in high-quality, peer-reviewed human clinical data
Nat Rev Cancer 18:377388
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