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They are not temporary interventions

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Nausea is typically most pronounced during dose escalation periods and often improves with continued treatment

Dermatological issues aside, tirzepatide can also cause bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site

But your body deserves better than survival mode

For long trips across many time zones, count actual hours from your last dose, not local clock days