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Cellular Aging & Longevity NAD+ is crucial for activating sirtuins, proteins that regulate aging and inflammation, and promote healthy cell function

Persistent fatigue, brain fog, low mood, weight gain, tingling in the hands or feet, frequent illness, post-COVID fatigue, or feeling generally "off" despite eating well and sleeping enough, especially if you're vegetarian, vegan, over 50, on metformin or a long-term acid reflux medication, or have a history of low B12 or pernicious anemia

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When calorie intake drops, it is common to notice lower energy, more fatigue, and reduced motivation

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