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Effets sur le poids corporel Un autre aspect extrmement intressant du mode daction des mimtiques du GLP-1 et du GIP est leur effet sur certains processus impliqus dans le contrle de lapptit (Figure 3)

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The human glucagon-like peptide-1 analogue liraglutide regulates pancreatic beta-cell proliferation and apoptosis via an AMPK/mTOR/P70S6K signaling pathway

These changes can sometimes trigger headaches

[18] Systemic side effects may include headache, irritability, restlessness, depression, fatigue, or edema resulting from fluid retention

Also, a generic version of Saxenda reached pharmacies in August 2025, and its 14% cheaper than Zepbound