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Tirzepatide decreases oral contraceptive exposure by about 20%, which increases the risk of pregnancy
Allan M Evans, Gianfranco Fornasini
Women told they likely couldn't conceive are getting pregnant on semaglutide
Important in every case: do not stop tirzepatide on your own
Last reviewed: May 14, 2026 Last updated: May 14, 2026 Written by: Jay Hastings , CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations
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