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Side Effects: Common Side Effects: Nausea, vomiting, diarrhoea, constipation and abdominal discomfort are common, particularly in the early weeks and after each dose increase

It is not known whether oral lipoic acid supplementation can slow cognitive decline related to aging or pathological conditions in humans

Typically, injections are given once a week or once every two weeks during the initial treatment phase

While analyses restricted to participants with established cardiovascular disease yielded MACE results that were directionally consistent with the overall analysis, conclusions are limited because subgroup estimates were based on trial-level reporting rather than individual participant data, and included studies continued to differ in patient characteristics, definitions of established cardiovascular disease, background therapies, and trial era

This hinted on liraglutide being an immune modulator that can alter macrophage phenotype

Alzheimer's research & therapy, 13(1), 112