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ClinicalTrials.gov registry entry NCT05669755 (2025) 8
For patients weighing 150 kg (330 pounds) or more, healthcare providers increase the dose to 1 gram to ensure adequate blood concentrations above the bacterial minimum inhibitory concentration for approximately 50 hours. This ceftriaxone monotherapy approach emerged after mounting azithromycin resistance prompted CDC to abandon dual-drug therapy in 2020, leaving gonorrhea treatment dependent on essentially one antibiotic classa precarious situation as resistance continues evolving globally
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Human S100A7 induces mature Interleukin1alpha expression by RAGE-p38 MAPK-Calpain1 pathway in psoriasis
A high-intensity exercise boot camp for persons with Parkinson disease: a phase II, pragmatic, randomized clinical trial of feasibility, safety, signal of efficacy, and disease mechanisms
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