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Structural Profile of AOD-9604 AOD-9604 consists of the sequence: Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe The two cysteine residues form a disulfide bond, creating a cyclic structure that enhances stability

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We summarize advances in research on urate -lowering drugs including urate transporter inhibitors, xanthine oxidase inhibitors as well as novel urate -lowering drugs, and evaluate the effect of urate-lowering therapy on the rate of hyperuricaemia-related diseases

To facilitate the clinical integration of emerging biomarkers in MASLD diagnosis and management, a flowchart summarizing the proposed stepwise implementation ranging from initial clinical assessment to biomarker-guided monitoring is presented in Figure 4

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Explore potential interactions across tissue structure, vascular signaling, and inflammation-related pathways