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Database screening revealed that the tyrosinase peptide 450462 shared a homologous amino acid sequence with the cytomegalovirus envelope glycoprotein H peptide (CMV-egH290-302), and further studies confirmed cross-reactive T cell responses between the two peptides (45, 46)

Oxidation of the Cys residue in the active site of PTPs by ROS abrogates its nucleophilic properties, thereby inhibiting PTP activity (87)

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