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8.9% with placebo.[1,4] During the trial, gastrointestinal adverse events were more frequent in the semaglutide group than in the placebo group

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Heart rate should be monitored at regular intervals consistent with usual clinical practice in patients taking semaglutide and patients should inform health care providers of palpitations or feelings of a racing heartbeat while at rest during semaglutide treatment

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At the end of the administration, we sacrificed the rats by intraperitoneal injection of 3% pentobarbital sodium (100 mg/kg), and the tissue samples were processed differently according to the different experimental protocols

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