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Mia really knows her stuff and takes the time to explain things properly
You may or may not see a faster drop on the scale, but your measurements and body composition will likely improve more than with tirzepatide alone
As a doctor, theres a lot of burden on your shoulders when you are prescribing something with insufficient evidence, but the patients insist on giving it a try. With no formal approvals surrounding their use from regulatory bodies like the Drugs Controller General of India (DCGI), they are considered off-label treatments
It does not interact with the hunger and satiety signaling pathways that tirzepatide and other GLP-1 agonists target
Furthermore, gene expression analysis of intestinal epithelial cells (IECs) showed no significant differences in mRNA levels of Gip and Glp1 and the potential upstream transcription factor regulatory factor X6 ( Rfx6 ) in duodenum, jejunum, ileum, and colon, while expression of pancreatic and duodenal homeobox 1 ( Pdx1 ) was higher in jejunum of PAR2-R38E mice when compared with PAR2-G37I and WT mice (Supplemental Figure 2C)
In theory, this sounds like a good self-regulating system
