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An athlete needing dialysis treatment requires a Therapeutic Use Exemption
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Patients with certain health conditions, such as heart failure, kidney disease, or high blood pressure, should approach IV hydration therapy with caution
Furthermore, the Philippines Food and Drug Administration (FDA) has sanctioned its application as an adjunctive treatment to mitigate the neurotoxic effects of cisplatin chemotherapy[3]
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Nevertheless, the homozygote mutant genotype leads to hyperhomocysteinemia only when plasma folate status is low in healthy subjects and in patients with cardiovascular disease, thus subjects with this MTHFR mutation may be sensitive to low folate intake (Christensen et al, 1997
