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Incorrect injection can cause pain, bruising, or swelling
This explains why some patients experience: Temporary bloating or joint discomfort from fluid shifts Increased hunger due to ghrelin pathway activation Changes in blood sugar regulation in susceptible individuals Patients with diabetes, insulin resistance, or other metabolic conditions require medical evaluation and appropriate monitoring before and during treatment
nonetheless, it is recommended that careful monitoring be performed
Around a fifth of the participants said that food tasted sweeter (21.3%) or saltier (22.6%) than before
Adverse events caused treatment discontinuation in 4.3%, 7.1%, 6.2%, and 2.6% of participants receiving 5-mg, 10-mg, 15-mg tirzepatide doses and placebo, respectively [49]
Pancreatitis was not reported in the RCTs (61)
