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Previous animal studies have revealed that noise exposure can induce immediate and permanent cochlear synaptopathy 18 , as evidenced by the fact that synaptic counts measured at 0 h post-exposure are similar to those seen at 24 h, 1 wk and 8 wks thereafter 16

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Conclusions To summarize, the 68-week treatment with coadministered cagrilintide and semaglutide resulted in substantial and clinically meaningful weight loss in adults with overweight or obesity, significantly outperforming monotherapies and placebo (- 5.5% vs

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