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With documented effects on collagen and elastin synthesis, matrix metalloproteinase regulation, wound healing, and a remarkably broad gene expression programme activating over 4,000 genes in human fibroblast studies
The IGF-1 receptor density on satellite cells is approximately twice that on mature myofibers, making satellite cells particularly sensitive to GH secretagogue-driven IGF-1 pulses 5
Mechanism investigation focuses on Akt-eNOS axis activation and sustained NO synthesis for neovascularization
J Pioneering Med Sci
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