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10.1016/j.plaphy.2020.09.008 Plant Physiol

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Patients with chronic stubborn midsection adiposity that has been resistant to conventional weight-loss approaches

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Compared with conventional GLP-1 receptor agonists, such as liraglutide and semaglutide, tirzepatide has demonstrated superior efficacy in body weight control in several phase III clinical trials, with average weight reductions exceeding 20% in some study populations (15)