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Moreover, Cys26 from the N-terminal segment and Cys584 from the IPT1 domain are closely adjacent to each other in our model, suggesting that they form a disulfide bond to further strengthen the interaction between these two structural motifs (Supplementary Fig

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Monitoring Protocol: Although the trials showed no concerning laboratory changes, prudent clinical practice suggests baseline and periodic monitoring of metabolic parameters, complete blood counts, liver function, and kidney function

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TB-500 is usually framed as the broader remodeling signal