GLP-1 in addiction medicine: GLP-1 acts on pancreas, gut, kidney, heart and thyroid receptors to activate reward/stress hubs (VTA, NAc, ARC, PFC, hypothalamus)
Circulating trimethylamine N-oxide in association with diet and cardiometabolic biomarkers: an international pooled analysis
Key Takeaways IGF-1 LR3 has a half-life of roughly 20 to 30 hours versus native IGF-1's roughly 12 to 15 hours, due to reduced binding protein affinity, giving it the strongest mechanistic case for direct anabolism among research peptides
The Lancet (2021) 6
There are substantial dangers in having these medications pulled away from patients, said Copeland
The role of dietary choline supplementation in adult patients with metabolic syndrome was examined in a randomized crossover intervention in 23 individuals supplemented with either 3 eggs/day or 400 mg choline per day for 3 weeks, followed by a 4-week washout, and then the alternate interventions (NCT03877003) (162)