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Downregulation of selenoprotein mRNAs including GPX3 97 , GPX1 , and GPX4 96,98 , and Selenop 99 was observed in human and mouse OA chondrocytes
Therefore, measuring GSH levels to determine the availability of cysteine as the limiting step must be considered in future studies
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The broad pattern for acute injuries and post-surgical contexts in the data sits between four and eight weeks
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