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BMJ 303 , 671675 (1991)

Future Research Directions and Emerging Applications Systemic Administration and Biodistribution Studies While most clinical applications of GHK-Cu involve topical administration, emerging research explores systemic delivery routes including subcutaneous injection, intravenous infusion, and oral administration for potential applications in systemic inflammation, tissue remodeling, and age-related decline

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8 weeks (0.251.0 mg/wk): ~1 vial 12 weeks (gradual to 1.7 mg/wk): ~2 vials 16 weeks (gradual to 2.44.5 mg/wk): ~3 vials Insulin Syringes (U-100, 1 mL) Per week: 1 syringe (once-weekly dosing) 12 weeks: 12 syringes 24 weeks: 24 syringes 48 weeks: 48 syringes Bacteriostatic Water (10 mL bottles) Use 2.0 mL (gradual) or 1.0 mL (advanced) per vial for reconstitution