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There are six residues that are mostly conserved in all Cys-GST classes, or at least in the sequences used for the alignment

Future research should explore integrative approaches that combine microbial modulation with immune and metabolic regulation, potentially enabling personalized and multi-pathway therapeutic strategies for patients with DKD

Journal of Physiology, Paris , 87 (5), 313327

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Expanding real-world data collection and employing advanced translational models will be important for evaluating the applicability and safety of SIRT1-based interventions across diverse metabolic phenotypes

Therefore, knockdown of ELAVL1 or CIRBP can inhibit ferritinophagy and thus suppress ferroptosis [153]