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Discard any vial showing signs of contamination, damage, or after 28 days of first use, whichever comes first
Its effects can last several hours, which is why evening use is discouraged.
Tan MW, Mahajan-Miklos S, Ausubel FM (1999) Killing of Caenorhabditis elegans by Pseudomonas aeruginosa used to model mammalian bacterial pathogenesis
doi:10.1159/000350185 Marx W, Ried K, McCarthy AL, et al
There are anecdotes suggesting that creatine has other side effects
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