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doi: 10.1038/s41467-020-14906-9

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Hess DT, Matsumoto A, Kim SO, Marshall HE, Stamler JS

Heads up: This is intended to be a spot treatment, so you may need to supplement it with another product for all-over brightening

For individuals with a body mass index (BMI) of 30 kg/m or above (or 27.5 kg/m for people from South Asian, Chinese, other Asian, Middle Eastern, Black African, or African-Caribbean backgrounds), NICE recommends considering pharmacological interventions alongside lifestyle changes when dietary and exercise modifications alone have been insufficient