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Contract makers like that the compound can be made in any amount, from small study batches of a few grams to the kilograms needed for clinical studies

Scientists isolated this specific 15-amino acid sequence because it demonstrated the most consistent biological activity in early experiments

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The National Institutes of Health (NIH) agrees with the FDA that cyanocobalamin is safe

Low-quality evidence from another trial that compared the effect of ALCAR (1.5 g/day) with that of methylcobalamin (1.5 mg/day) for 24 weeks suggested no difference between treatments regarding the extent of functional disability (using the Neuropathy Disability Scale) or measures of symptom quality and severity (using the Neuropathy Symptom Scale) (89)