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Historically, treatment options have been limited to lifestyle modificationspecifically weight loss of 710% of body weight, which can improve hepatic steatosis and inflammation

In the bioactive ingredient isoflavone class, daidzein, genistein, galycosin, and prunetin were identified

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Subcutaneous semaglutide was FDA approved as Ozempic to treat type 2 diabetes in 2017

To overcome this, we utilized 3D structures generated by AlphaFold [37], though this approach may have contributed to the higher frequency of non-affected proteins predicted by Missense3D tool

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