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(2006) Prolonged Stimulation of GH and IGF-1 Secretion by CJC-1295, a Long-Acting Analog of GHRH, in Healthy Adults J Clin Endocrinol Metab 91(3):799805

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That short window is the source of both its strengths and its limitations: Strength: the GH pulse it produces closely mirrors what your body would do naturally

(2) During drug development, it is necessary to address the issues of drug targeting and delivery to ensure that drugs act accurately on this axis while avoiding the effects on normal cells and physiological processes

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Sugatani J, Noguchi Y, Hattori Y, Yamaguchi M, Yamazaki Y, Ikari A (2016) Threonine-408 regulates the stability of human pregnane X receptor through its phosphorylation and the CHIP/chaperone-autophagy pathway