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Sci Rep 15 , 34673 (2025)
The findings suggest that GLP-1s may deliver meaningful improvements in both disease severity and patient-reported quality of life
The body must convert cyanocobalamin through several steps before it becomes biologically active
Human clinical trial data remains limited, with Phase I and II trials for inflammatory bowel disease conducted in the 1990s claiming safety with no toxicity, though full peer-reviewed data never appeared in scientific literature
Clinical trials like STEP 1 showed participants lost an average of 14.9% body weight over 68 weeks
The phase 2 and phase 3 trials focused primarily on total body weight reduction
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