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However, basal levels of phase I and most phase II drug metabolizing enzymes in HepG2 cells are very low compared to human hepatocytes (Wilkening et al., 2003
Maintaining 10 or more rotation sites for frequent dosing allows adequate tissue recovery between injections
600mg / 1200mg
35 Chronic toxicities are manifested as conditions that develop over extended periods from chronic exposure to relatively low concentrations (eg, sustained environmental exposure)
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