fda warning glp-1 compounding september 2025 Beyond the Headlines: Letters to Compounders Safe use of compounded GLP

Dose titration during the first week prevents common adverse events

B., Grassian, V

These processes are essential for gut repair

For patients seeking additional weight loss, microdosing is generally less effective than standard therapeutic dosing

For compounding pharmacies or physicians that have been compounding semaglutide products during the shortage, the FDA has set clear deadlines for ceasing general semaglutide compounding practices: State-licensed pharmacies or physicians compounding semaglutide under Section 503A of the FD&C Act must stop compounding, distributing, or dispensing semaglutide injections that are essentially copies of an FDA-approved product by April 22, 2025

LDN has two downsides: It requires a doctors prescription and must be purchased from a compounding pharmacy